Autocrine CSF-1R signaling drives mesothelioma chemoresistance via AKT activation

Clinical management of malignant pleural mesothelioma (MPM) is very challenging because of the uncommon resistance of this tumor to chemotherapy. We report here increased expression of macrophage colony-stimulating-factor-1-receptor (M-CSF/CSF-1R) mRNA in mesothelioma versus normal tissue specimens...

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Detalles Bibliográficos
Autores principales: Cioce, M, Canino, C, Goparaju, C, Yang, H, Carbone, M, Pass, H I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424113/
https://www.ncbi.nlm.nih.gov/pubmed/24722292
http://dx.doi.org/10.1038/cddis.2014.136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424113/
https://www.ncbi.nlm.nih.gov/pubmed/24722292
http://dx.doi.org/10.1038/cddis.2014.136

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