Stat3 regulates centrosome clustering in cancer cells via Stathmin/PLK1

Cancer cells frequently have amplified centrosomes that must be clustered together to form a bipolar mitotic spindle, and targeting centrosome clustering is considered a promising therapeutic strategy. A high-content chemical screen for inhibitors of centrosome clustering identified Stattic, a Stat3...

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Detalles Bibliográficos
Autores principales: Morris, Edward J., Kawamura, Eiko, Gillespie, Jordan A., Balgi, Aruna, Kannan, Nagarajan, Muller, William J., Roberge, Michel, Dedhar, Shoukat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424153/
https://www.ncbi.nlm.nih.gov/pubmed/28474672
http://dx.doi.org/10.1038/ncomms15289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424153/
https://www.ncbi.nlm.nih.gov/pubmed/28474672
http://dx.doi.org/10.1038/ncomms15289

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