Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer

Single-cell transcriptome profiling of tumour tissue isolates allows the characterization of heterogeneous tumour cells along with neighbouring stromal and immune cells. Here we adopt this powerful approach to breast cancer and analyse 515 cells from 11 patients. Inferred copy number variations from...

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Detalles Bibliográficos
Autores principales: Chung, Woosung, Eum, Hye Hyeon, Lee, Hae-Ock, Lee, Kyung-Min, Lee, Han-Byoel, Kim, Kyu-Tae, Ryu, Han Suk, Kim, Sangmin, Lee, Jeong Eon, Park, Yeon Hee, Kan, Zhengyan, Han, Wonshik, Park, Woong-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424158/
https://www.ncbi.nlm.nih.gov/pubmed/28474673
http://dx.doi.org/10.1038/ncomms15081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424158/
https://www.ncbi.nlm.nih.gov/pubmed/28474673
http://dx.doi.org/10.1038/ncomms15081

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