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Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer
Single-cell transcriptome profiling of tumour tissue isolates allows the characterization of heterogeneous tumour cells along with neighbouring stromal and immune cells. Here we adopt this powerful approach to breast cancer and analyse 515 cells from 11 patients. Inferred copy number variations from...
Autores principales: | Chung, Woosung, Eum, Hye Hyeon, Lee, Hae-Ock, Lee, Kyung-Min, Lee, Han-Byoel, Kim, Kyu-Tae, Ryu, Han Suk, Kim, Sangmin, Lee, Jeong Eon, Park, Yeon Hee, Kan, Zhengyan, Han, Wonshik, Park, Woong-Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424158/ https://www.ncbi.nlm.nih.gov/pubmed/28474673 http://dx.doi.org/10.1038/ncomms15081 |
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