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Digitally Barcoding Mycobacterium tuberculosis Reveals In Vivo Infection Dynamics in the Macaque Model of Tuberculosis

Infection with Mycobacterium tuberculosis causes a spectrum of outcomes; the majority of individuals contain but do not eliminate the infection, while a small subset present with primary active tuberculosis (TB) disease. This variability in infection outcomes is recapitulated at the granuloma level...

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Detalles Bibliográficos
Autores principales: Martin, Constance J., Cadena, Anthony M., Leung, Vivian W., Lin, Philana Ling, Maiello, Pauline, Hicks, Nathan, Chase, Michael R., Flynn, JoAnne L., Fortune, Sarah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424202/
https://www.ncbi.nlm.nih.gov/pubmed/28487426
http://dx.doi.org/10.1128/mBio.00312-17