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Differentiation of mesenchymal stem cells into cardiomyocytes is regulated by miRNA-1-2 via WNT signaling pathway

BACKGROUND: Bone marrow derived stem cells (BMSCs) have the potential to differentiate into cardiomyocytes, but the rate of differentiation is low and the mechanism of differentiation is unclear completely. Here, we aimed to investigate the role of miR1-2 in differentiation of mouse BMSCs into cardi...

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Detalles Bibliográficos
Autores principales: Shen, Xing, Pan, Bo, Zhou, Huiming, Liu, Lingjuan, Lv, Tiewei, Zhu, Jing, Huang, Xupei, Tian, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424345/
https://www.ncbi.nlm.nih.gov/pubmed/28490365
http://dx.doi.org/10.1186/s12929-017-0337-9