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Binding of Plasmodium falciparum to CD36 can be shielded by the glycocalyx

BACKGROUND: Plasmodium falciparum-infected erythrocytes sequester in the microcirculation due to interaction between surface-expressed parasite proteins and endothelial receptors. Endothelial cells are covered in a carbohydrate-rich glycocalyx that shields against undesired leukocyte adhesion. It wa...

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Detalles Bibliográficos
Autores principales: Hempel, Casper, Wang, Christian William, Kurtzhals, Jørgen Anders Lindholm, Staalsø, Trine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424350/
https://www.ncbi.nlm.nih.gov/pubmed/28486940
http://dx.doi.org/10.1186/s12936-017-1844-6