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ULK1 phosphorylates Sec23A and mediates autophagy-induced inhibition of ER-to-Golgi traffic

BACKGROUND: Autophagy is an inducible autodigestive process that allows cells to recycle proteins and other materials for survival during stress and nutrient deprived conditions. The kinase ULK1 is required to activate this process. ULK1 phosphorylates a number of target proteins and regulates many...

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Detalles Bibliográficos
Autores principales: Gan, Wenjia, Zhang, Caiyun, Siu, Ka Yu, Satoh, Ayano, Tanner, Julian A., Yu, Sidney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424413/
https://www.ncbi.nlm.nih.gov/pubmed/28486929
http://dx.doi.org/10.1186/s12860-017-0138-8