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ULK1 phosphorylates Sec23A and mediates autophagy-induced inhibition of ER-to-Golgi traffic
BACKGROUND: Autophagy is an inducible autodigestive process that allows cells to recycle proteins and other materials for survival during stress and nutrient deprived conditions. The kinase ULK1 is required to activate this process. ULK1 phosphorylates a number of target proteins and regulates many...
Autores principales: | Gan, Wenjia, Zhang, Caiyun, Siu, Ka Yu, Satoh, Ayano, Tanner, Julian A., Yu, Sidney |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424413/ https://www.ncbi.nlm.nih.gov/pubmed/28486929 http://dx.doi.org/10.1186/s12860-017-0138-8 |
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