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Macrocycles: lessons from the distant past, recent developments, and future directions
A noticeable increase in molecular complexity of drug targets has created an unmet need in the therapeutic agents that are larger than traditional small molecules. Macrocycles, which are cyclic compounds comprising 12 atoms or more, are now recognized as molecules that “are up to the task” to interr...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Royal Society of Chemistry
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424464/ https://www.ncbi.nlm.nih.gov/pubmed/28553456 http://dx.doi.org/10.1039/c4sc03089c |