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Designing logical codon reassignment – Expanding the chemistry in biology

Over the last decade, the ability to genetically encode unnatural amino acids (UAAs) has evolved rapidly. The programmed incorporation of UAAs into recombinant proteins relies on the reassignment or suppression of canonical codons with an amino-acyl tRNA synthetase/tRNA (aaRS/tRNA) pair, selective f...

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Detalles Bibliográficos
Autores principales: Dumas, Anaëlle, Lercher, Lukas, Spicer, Christopher D., Davis, Benjamin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424465/
https://www.ncbi.nlm.nih.gov/pubmed/28553457
http://dx.doi.org/10.1039/c4sc01534g