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Catalytic asymmetric synthesis of CF(3)-substituted tertiary propargylic alcohols via direct aldol reaction of α-N(3) amide

Organofluorine compounds are found in several important classes of chemicals, such as pharmaceuticals, agrochemicals, and functional materials. Chemists have been immensely interested in the development of methodologies for expeditious access to fluorine containing building blocks. In this study, we...

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Detalles Bibliográficos
Autores principales: Noda, Hidetoshi, Amemiya, Fuyuki, Weidner, Karin, Kumagai, Naoya, Shibasaki, Masakatsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424470/
https://www.ncbi.nlm.nih.gov/pubmed/28553529
http://dx.doi.org/10.1039/c7sc00330g