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Catalytic asymmetric synthesis of CF(3)-substituted tertiary propargylic alcohols via direct aldol reaction of α-N(3) amide
Organofluorine compounds are found in several important classes of chemicals, such as pharmaceuticals, agrochemicals, and functional materials. Chemists have been immensely interested in the development of methodologies for expeditious access to fluorine containing building blocks. In this study, we...
Autores principales: | Noda, Hidetoshi, Amemiya, Fuyuki, Weidner, Karin, Kumagai, Naoya, Shibasaki, Masakatsu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424470/ https://www.ncbi.nlm.nih.gov/pubmed/28553529 http://dx.doi.org/10.1039/c7sc00330g |
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