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Platelet Shape Changes and Cytoskeleton Dynamics as Novel Therapeutic Targets for Anti-Thrombotic Drugs

Platelets play an essential role in hemostasis through aggregation and adhesion to vascular injury sites but their unnecessary activation can often lead to thrombotic diseases. Upon exposure to physical or biochemical stimuli, remarkable platelet shape changes precede aggregation or adhesion. Platel...

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Detalles Bibliográficos
Autores principales: Shin, Eun-Kyung, Park, Hanseul, Noh, Ji-Yoon, Lim, Kyung-Min, Chung, Jin-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424631/
https://www.ncbi.nlm.nih.gov/pubmed/27871158
http://dx.doi.org/10.4062/biomolther.2016.138