Molecular Signature That Determines the Acute Tolerance of G Protein-Coupled Receptors

Desensitization and acute tolerance are terms used to describe the attenuation of receptor responsiveness by prolonged or intermittent exposure to an agonist. Unlike desensitization of G protein-coupled receptors (GPCRs), which is commonly explained by steric hindrance caused by the β-arrestins that...

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Detalles Bibliográficos
Autores principales: Min, Chengchun, Zhang, Xiaohan, Zheng, Mei, Sun, Ningning, Acharya, Srijan, Zhang, Xiaowei, Kim, Kyeong-Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424633/
https://www.ncbi.nlm.nih.gov/pubmed/27956717
http://dx.doi.org/10.4062/biomolther.2016.193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424633/
https://www.ncbi.nlm.nih.gov/pubmed/27956717
http://dx.doi.org/10.4062/biomolther.2016.193

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