Cargando…

Intravenous Administration of Substance P Attenuates Mechanical Allodynia Following Nerve Injury by Regulating Neuropathic Pain-Related Factors

This study aimed to investigate the analgesic effect of substance P (SP) in an animal model of neuropathic pain. An experimental model of neuropathic pain, the chronic constriction injury (CCI) model, was established using ICR mice. An intravenous (i.v.) injection of SP (1 nmole/kg) was administered...

Descripción completa

Detalles Bibliográficos
Autores principales: Chung, Eunkyung, Yoon, Tae Gyoon, Kim, Sumin, Kang, Moonkyu, Kim, Hyun Jeong, Son, Youngsook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424635/
https://www.ncbi.nlm.nih.gov/pubmed/27956715
http://dx.doi.org/10.4062/biomolther.2016.137