A Novel Urotensin II Receptor Antagonist, KR-36996 Inhibits Smooth Muscle Proliferation through ERK/ROS Pathway

Urotensin II (UII) is a mitogenic and hypertrophic agent that can induce the proliferation of vascular cells. UII inhibition has been considered as beneficial strategy for atherosclerosis and restenosis. However, currently there is no therapeutics clinically available for atherosclerosis or restenos...

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Detalles Bibliográficos
Autores principales: Kim, Tae-Ho, Lee, Dong Gil, Kim, Young-Ae, Lee, Byung Ho, Yi, Kyu Yang, Jung, Yi-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424641/
https://www.ncbi.nlm.nih.gov/pubmed/28173642
http://dx.doi.org/10.4062/biomolther.2016.219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424641/
https://www.ncbi.nlm.nih.gov/pubmed/28173642
http://dx.doi.org/10.4062/biomolther.2016.219

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