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A Novel Urotensin II Receptor Antagonist, KR-36996 Inhibits Smooth Muscle Proliferation through ERK/ROS Pathway
Urotensin II (UII) is a mitogenic and hypertrophic agent that can induce the proliferation of vascular cells. UII inhibition has been considered as beneficial strategy for atherosclerosis and restenosis. However, currently there is no therapeutics clinically available for atherosclerosis or restenos...
Autores principales: | Kim, Tae-Ho, Lee, Dong Gil, Kim, Young-Ae, Lee, Byung Ho, Yi, Kyu Yang, Jung, Yi-Sook |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424641/ https://www.ncbi.nlm.nih.gov/pubmed/28173642 http://dx.doi.org/10.4062/biomolther.2016.219 |
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