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Distribution and cluster analysis of predicted intrinsically disordered protein Pfam domains

The Pfam database groups regions of proteins by how well hidden Markov models (HMMs) can be trained to recognize similarities among them. Conservation pressure is probably in play here. The Pfam seed training set includes sequence and structure information, being drawn largely from the PDB. A long s...

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Detalles Bibliográficos
Autores principales: Williams, Robert W, Xue, Bin, Uversky, Vladimir N, Dunker, A Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424788/
https://www.ncbi.nlm.nih.gov/pubmed/28516017
http://dx.doi.org/10.4161/idp.25724