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Extracting structural information from charge-state distributions of intrinsically disordered proteins by non-denaturing electrospray-ionization mass spectrometry

Intrinsically disordered proteins (IDPs) exert key biological functions but tend to escape identification and characterization due to their high structural dynamics and heterogeneity. The possibility to dissect conformational ensembles by electrospray-ionization mass spectrometry (ESI-MS) offers an...

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Detalles Bibliográficos
Autores principales: Testa, Lorenzo, Brocca, Stefania, Santambrogio, Carlo, D’Urzo, Annalisa, Habchi, Johnny, Longhi, Sonia, Uversky, Vladimir N, Grandori, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424789/
https://www.ncbi.nlm.nih.gov/pubmed/28516012
http://dx.doi.org/10.4161/idp.25068