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Extracting structural information from charge-state distributions of intrinsically disordered proteins by non-denaturing electrospray-ionization mass spectrometry
Intrinsically disordered proteins (IDPs) exert key biological functions but tend to escape identification and characterization due to their high structural dynamics and heterogeneity. The possibility to dissect conformational ensembles by electrospray-ionization mass spectrometry (ESI-MS) offers an...
Autores principales: | Testa, Lorenzo, Brocca, Stefania, Santambrogio, Carlo, D’Urzo, Annalisa, Habchi, Johnny, Longhi, Sonia, Uversky, Vladimir N, Grandori, Rita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424789/ https://www.ncbi.nlm.nih.gov/pubmed/28516012 http://dx.doi.org/10.4161/idp.25068 |
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