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A coordinated DNA damage response promotes adult quiescent neural stem cell activation

Stem and differentiated cells frequently differ in their response to DNA damage, which can determine tissue sensitivity. By exploiting insight into the spatial arrangement of subdomains within the adult neural subventricular zone (SVZ) in vivo, we show distinct responses to ionising radiation (IR) b...

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Detalles Bibliográficos
Autores principales: Barazzuol, Lara, Ju, Limei, Jeggo, Penny A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424956/
https://www.ncbi.nlm.nih.gov/pubmed/28489848
http://dx.doi.org/10.1371/journal.pbio.2001264