Contribution of thrombin-reactive brain pericytes to blood-brain barrier dysfunction in an in vivo mouse model of obesity-associated diabetes and an in vitro rat model

Diabetic complications are characterized by the dysfunction of pericytes located around microvascular endothelial cells. The blood–brain barrier (BBB) exhibits hyperpermeability with progression of diabetes. Therefore, brain pericytes at the BBB may be involved in diabetic complications of the centr...

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Detalles Bibliográficos
Autores principales: Machida, Takashi, Takata, Fuyuko, Matsumoto, Junichi, Miyamura, Tomoyuki, Hirata, Ryosuke, Kimura, Ikuya, Kataoka, Yasufumi, Dohgu, Shinya, Yamauchi, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425209/
https://www.ncbi.nlm.nih.gov/pubmed/28489922
http://dx.doi.org/10.1371/journal.pone.0177447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425209/
https://www.ncbi.nlm.nih.gov/pubmed/28489922
http://dx.doi.org/10.1371/journal.pone.0177447

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