CaMKIIα may modulate fentanyl-induced hyperalgesia via a CeLC-PAG-RVM-spinal cord descending facilitative pain pathway in rats

Each of the lateral capsular division of central nucleus of amygdala(CeLC), periaqueductal gray (PAG), rostral ventromedial medulla(RVM) and spinal cord has been proved to contribute to the development of opioid-induced hyperalgesia(OIH). Especially, Ca(2+)/calmodulin-dependent protein kinase IIα (C...

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Detalles Bibliográficos
Autores principales: Li, Zhen, Yin, Pingping, Chen, Jian, Jin, Shenglan, Liu, Jieqiong, Luo, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425219/
https://www.ncbi.nlm.nih.gov/pubmed/28489932
http://dx.doi.org/10.1371/journal.pone.0177412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425219/
https://www.ncbi.nlm.nih.gov/pubmed/28489932
http://dx.doi.org/10.1371/journal.pone.0177412

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