Analysis of global DNA methylation changes in primary human fibroblasts in the early phase following X-ray irradiation

Epigenetic alterations may contribute to the generation of cancer cells in a multi-step process of tumorigenesis following irradiation of normal body cells. Primary human fibroblasts with intact cell cycle checkpoints were used as a model to test whether X-ray irradiation with 2 and 4 Gray induces d...

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Detalles Bibliográficos
Autores principales: Maierhofer, Anna, Flunkert, Julia, Dittrich, Marcus, Müller, Tobias, Schindler, Detlev, Nanda, Indrajit, Haaf, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425224/
https://www.ncbi.nlm.nih.gov/pubmed/28489894
http://dx.doi.org/10.1371/journal.pone.0177442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425224/
https://www.ncbi.nlm.nih.gov/pubmed/28489894
http://dx.doi.org/10.1371/journal.pone.0177442

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