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Analysis of global DNA methylation changes in primary human fibroblasts in the early phase following X-ray irradiation
Epigenetic alterations may contribute to the generation of cancer cells in a multi-step process of tumorigenesis following irradiation of normal body cells. Primary human fibroblasts with intact cell cycle checkpoints were used as a model to test whether X-ray irradiation with 2 and 4 Gray induces d...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425224/ https://www.ncbi.nlm.nih.gov/pubmed/28489894 http://dx.doi.org/10.1371/journal.pone.0177442 |