Epstein-Barr virus ensures B cell survival by uniquely modulating apoptosis at early and late times after infection

Latent Epstein-Barr virus (EBV) infection is causally linked to several human cancers. EBV expresses viral oncogenes that promote cell growth and inhibit the apoptotic response to uncontrolled proliferation. The EBV oncoprotein LMP1 constitutively activates NFκB and is critical for survival of EBV-i...

Descripción completa

Detalles Bibliográficos
Autores principales: Price, Alexander M, Dai, Joanne, Bazot, Quentin, Patel, Luv, Nikitin, Pavel A, Djavadian, Reza, Winter, Peter S, Salinas, Cristina A, Barry, Ashley Perkins, Wood, Kris C, Johannsen, Eric C, Letai, Anthony, Allday, Martin J, Luftig, Micah A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425254/
https://www.ncbi.nlm.nih.gov/pubmed/28425914
http://dx.doi.org/10.7554/eLife.22509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425254/
https://www.ncbi.nlm.nih.gov/pubmed/28425914
http://dx.doi.org/10.7554/eLife.22509

Ejemplares similares