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Epstein-Barr virus ensures B cell survival by uniquely modulating apoptosis at early and late times after infection

Latent Epstein-Barr virus (EBV) infection is causally linked to several human cancers. EBV expresses viral oncogenes that promote cell growth and inhibit the apoptotic response to uncontrolled proliferation. The EBV oncoprotein LMP1 constitutively activates NFκB and is critical for survival of EBV-i...

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Detalles Bibliográficos
Autores principales: Price, Alexander M, Dai, Joanne, Bazot, Quentin, Patel, Luv, Nikitin, Pavel A, Djavadian, Reza, Winter, Peter S, Salinas, Cristina A, Barry, Ashley Perkins, Wood, Kris C, Johannsen, Eric C, Letai, Anthony, Allday, Martin J, Luftig, Micah A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425254/
https://www.ncbi.nlm.nih.gov/pubmed/28425914
http://dx.doi.org/10.7554/eLife.22509

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