Cargando…
Epstein-Barr virus ensures B cell survival by uniquely modulating apoptosis at early and late times after infection
Latent Epstein-Barr virus (EBV) infection is causally linked to several human cancers. EBV expresses viral oncogenes that promote cell growth and inhibit the apoptotic response to uncontrolled proliferation. The EBV oncoprotein LMP1 constitutively activates NFκB and is critical for survival of EBV-i...
Autores principales: | Price, Alexander M, Dai, Joanne, Bazot, Quentin, Patel, Luv, Nikitin, Pavel A, Djavadian, Reza, Winter, Peter S, Salinas, Cristina A, Barry, Ashley Perkins, Wood, Kris C, Johannsen, Eric C, Letai, Anthony, Allday, Martin J, Luftig, Micah A |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425254/ https://www.ncbi.nlm.nih.gov/pubmed/28425914 http://dx.doi.org/10.7554/eLife.22509 |
Ejemplares similares
-
Epstein-Barr Virus (EBV) Latent Protein EBNA3A Directly Targets and Silences the STK39 Gene in B Cells Infected by EBV
por: Bazot, Quentin, et al.
Publicado: (2018) -
Recent advances in understanding Epstein-Barr virus
por: Stanfield, Brent A., et al.
Publicado: (2017) -
Requirement for PRC1 subunit BMI1 in host gene activation by Epstein–Barr virus protein EBNA3C
por: Paschos, Kostas, et al.
Publicado: (2019) -
To Be or Not IIb: A Multi-Step Process for Epstein-Barr Virus Latency Establishment and Consequences for B Cell Tumorigenesis
por: Price, Alexander M., et al.
Publicado: (2015) -
Core binding factor (CBF) is required for Epstein-Barr virus EBNA3 proteins to regulate target gene expression
por: Paschos, Kostas, et al.
Publicado: (2017)