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RhoD Inhibits RhoC-ROCK-Dependent Cell Contraction via PAK6

RhoA-mediated regulation of myosin-II activity in the actin cortex controls the ability of cells to contract and bleb during a variety of cellular processes, including cell migration and division. Cell contraction and blebbing also frequently occur as part of the cytopathic effect seen during many d...

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Detalles Bibliográficos
Autores principales: Durkin, Charlotte H., Leite, Flavia, Cordeiro, João V., Handa, Yutaka, Arakawa, Yoshiki, Valderrama, Ferran, Way, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425256/
https://www.ncbi.nlm.nih.gov/pubmed/28486133
http://dx.doi.org/10.1016/j.devcel.2017.04.010