Neonatal Mice with Necrotizing Enterocolitis-like Injury Develop Thrombocytopenia despite Increased Megakaryopoiesis

BACKGROUND: Thrombocytopenia is frequently encountered in infants with necrotizing enterocolitis (NEC). To develop a preclinical model of NEC-related thrombocytopenia, we measured serial platelet counts in 10-day-old (P10) mouse pups with trinitrobenzene sulfonic acid (TNBS)-induced NEC-like injury....

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Detalles Bibliográficos
Autores principales: Namachivayam, Kopperuncholan, MohanKumar, Krishnan, Garg, Lalit, Torres, Benjamin A., Maheshwari, Akhil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425334/
https://www.ncbi.nlm.nih.gov/pubmed/28085792
http://dx.doi.org/10.1038/pr.2017.7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425334/
https://www.ncbi.nlm.nih.gov/pubmed/28085792
http://dx.doi.org/10.1038/pr.2017.7

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