Leucine-Rich Repeat Kinase 2 (LRRK2) Stimulates IL-1β-Mediated Inflammatory Signaling through Phosphorylation of RCAN1

Leucine-rich repeat kinase 2 (LRRK2) is a Ser/Thr kinase having mixed lineage kinase-like and GTPase domains, controlling neurite outgrowth and neuronal cell death. Evidence suggests that LRRK2 is involved in innate immune response signaling, but the underlying mechanism is yet unknown. A novel prot...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Kyung A., Yoo, Lang, Sung, Jee Y., Chung, Sun A., Um, Ji W., Kim, Hyeyoung, Seol, Wongi, Chung, Kwang C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425608/
https://www.ncbi.nlm.nih.gov/pubmed/28553204
http://dx.doi.org/10.3389/fncel.2017.00125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425608/
https://www.ncbi.nlm.nih.gov/pubmed/28553204
http://dx.doi.org/10.3389/fncel.2017.00125

Ejemplares similares