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Leucine-Rich Repeat Kinase 2 (LRRK2) Stimulates IL-1β-Mediated Inflammatory Signaling through Phosphorylation of RCAN1

Leucine-rich repeat kinase 2 (LRRK2) is a Ser/Thr kinase having mixed lineage kinase-like and GTPase domains, controlling neurite outgrowth and neuronal cell death. Evidence suggests that LRRK2 is involved in innate immune response signaling, but the underlying mechanism is yet unknown. A novel prot...

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Detalles Bibliográficos
Autores principales:	Han, Kyung A., Yoo, Lang, Sung, Jee Y., Chung, Sun A., Um, Ji W., Kim, Hyeyoung, Seol, Wongi, Chung, Kwang C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425608/ https://www.ncbi.nlm.nih.gov/pubmed/28553204 http://dx.doi.org/10.3389/fncel.2017.00125

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