Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs

Chronic inflammatory diseases such as arthritis are characterized by dysregulated responses to pro-inflammatory cytokines such as interleukin-1 (IL-1) and tumor necrosis factor α (TNF-α). Pharmacologic anti-cytokine therapies are often effective at diminishing this inflammatory response but have sig...

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Detalles Bibliográficos
Autores principales: Brunger, Jonathan M., Zutshi, Ananya, Willard, Vincent P., Gersbach, Charles A., Guilak, Farshid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425682/
https://www.ncbi.nlm.nih.gov/pubmed/28457885
http://dx.doi.org/10.1016/j.stemcr.2017.03.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425682/
https://www.ncbi.nlm.nih.gov/pubmed/28457885
http://dx.doi.org/10.1016/j.stemcr.2017.03.022

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