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Context-Dependent Functions of NANOG Phosphorylation in Pluripotency and Reprogramming

The core pluripotency transcription factor NANOG is critical for embryonic stem cell (ESC) self-renewal and somatic cell reprogramming. Although NANOG is phosphorylated at multiple residues, the role of NANOG phosphorylation in ESC self-renewal is incompletely understood, and no information exists r...

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Detalles Bibliográficos
Autores principales: Saunders, Arven, Li, Dan, Faiola, Francesco, Huang, Xin, Fidalgo, Miguel, Guallar, Diana, Ding, Junjun, Yang, Fan, Xu, Yang, Zhou, Hongwei, Wang, Jianlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425684/
https://www.ncbi.nlm.nih.gov/pubmed/28457890
http://dx.doi.org/10.1016/j.stemcr.2017.03.023