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Single-Cell Dynamic Analysis of Mitosis in Haploid Embryonic Stem Cells Shows the Prolonged Metaphase and Its Association with Self-diploidization

The recent establishment of mammalian haploid embryonic stem cells (ESCs) provides new possibilities for genetic screening and for understanding genome evolution and function. However, the dynamics of mitosis in haploid ESCs is still unclear. Here, we report that the duration of mitosis in haploid E...

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Detalles Bibliográficos
Autores principales: Guo, Ao, Huang, Shichao, Yu, Jiali, Wang, Huihan, Li, Haisen, Pei, Gang, Shen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425685/
https://www.ncbi.nlm.nih.gov/pubmed/28457886
http://dx.doi.org/10.1016/j.stemcr.2017.03.025