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Implementation of Isavuconazole in a Fluorescence-Based High-Performance Liquid Chromatography Kit Allowing Simultaneous Detection of All Four Currently Licensed Mold-Active Triazoles

Isavuconazole (ISZ) is a newly available broad-spectrum triazole agent recently approved for the treatment of both invasive aspergillosis and mucormycosis. The aim of this study was to develop a simple and reliable method for therapeutic drug monitoring (TDM) of ISZ in human plasma samples. The meth...

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Detalles Bibliográficos
Autores principales: Jørgensen, René, Andersen, Siri Rytcher, Astvad, Karen Marie Thyssen, Arendrup, Maiken Cavling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425791/
https://www.ncbi.nlm.nih.gov/pubmed/28497121
http://dx.doi.org/10.1128/mSphere.00098-17