In Vitro Evaluations and In Vivo Toxicity and Efficacy Studies of MFM501 against MRSA

Previously we have discovered a synthetically derived pyrrolidone alkaloid, MFM501, exhibiting good inhibitory activity against 53 MRSA and MSSA isolates with low cytotoxicity against three normal cell-lines with IC(50) values at >625 µg/ml. Time-kill assay, scanning electron microscopy (SEM) ana...

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Detalles Bibliográficos
Autores principales: Johari, Saiful Azmi, Mohtar, Mastura, Syed Mohamad, Sharifah Aminah, Mohammat, Mohd Fazli, Sahdan, Rohana, Mohamed, Azman, Mohamad Ridhwan, Mohamad Jemain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425839/
https://www.ncbi.nlm.nih.gov/pubmed/28536702
http://dx.doi.org/10.1155/2017/8032865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425839/
https://www.ncbi.nlm.nih.gov/pubmed/28536702
http://dx.doi.org/10.1155/2017/8032865

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