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In Vitro Evaluations and In Vivo Toxicity and Efficacy Studies of MFM501 against MRSA
Previously we have discovered a synthetically derived pyrrolidone alkaloid, MFM501, exhibiting good inhibitory activity against 53 MRSA and MSSA isolates with low cytotoxicity against three normal cell-lines with IC(50) values at >625 µg/ml. Time-kill assay, scanning electron microscopy (SEM) ana...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425839/ https://www.ncbi.nlm.nih.gov/pubmed/28536702 http://dx.doi.org/10.1155/2017/8032865 |