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Prediction of gene expression with cis-SNPs using mixed models and regularization methods

BACKGROUND: It has been shown that gene expression in human tissues is heritable, thus predicting gene expression using only SNPs becomes possible. The prediction of gene expression can offer important implications on the genetic architecture of individual functional associated SNPs and further inte...

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Detalles Bibliográficos
Autores principales: Zeng, Ping, Zhou, Xiang, Huang, Shuiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425981/
https://www.ncbi.nlm.nih.gov/pubmed/28490319
http://dx.doi.org/10.1186/s12864-017-3759-6