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Prediction of gene expression with cis-SNPs using mixed models and regularization methods
BACKGROUND: It has been shown that gene expression in human tissues is heritable, thus predicting gene expression using only SNPs becomes possible. The prediction of gene expression can offer important implications on the genetic architecture of individual functional associated SNPs and further inte...
Autores principales: | Zeng, Ping, Zhou, Xiang, Huang, Shuiping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425981/ https://www.ncbi.nlm.nih.gov/pubmed/28490319 http://dx.doi.org/10.1186/s12864-017-3759-6 |
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