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Astaxanthin protects astrocytes against trauma-induced apoptosis through inhibition of NKCC1 expression via the NF-κB signaling pathway

BACKGROUND: Astaxanthin (ATX) is a carotenoid pigment with pleiotropic pharmacological properties that is seen as a possible drug for treating cerebral ischemic injury and subarachnoid hemorrhage. Na(+)–K(+)–2Cl(−) co-transporter-1 (NKCC1), an intrinsic membrane protein expressed by many cell types,...

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Detalles Bibliográficos
Autores principales: Zhang, Mingkun, Cui, Zhenwen, Cui, Hua, Wang, Yong, Zhong, Chunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425995/
https://www.ncbi.nlm.nih.gov/pubmed/28490320
http://dx.doi.org/10.1186/s12868-017-0358-z