Epigenetic modifications of the immune-checkpoint genes CTLA4 and PDCD1 in non-small cell lung cancer results in increased expression

Targeting checkpoint inhibitors using monoclonal antibodies results in significantly better outcome of cancer patients compared to conventional chemotherapy. However, the current companion diagnostics to predict response is so far suboptimal, since they base on more or less reliable immunohistochemi...

Descripción completa

Detalles Bibliográficos
Autores principales: Marwitz, Sebastian, Scheufele, Swetlana, Perner, Sven, Reck, Martin, Ammerpohl, Ole, Goldmann, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426039/
https://www.ncbi.nlm.nih.gov/pubmed/28503213
http://dx.doi.org/10.1186/s13148-017-0354-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426039/
https://www.ncbi.nlm.nih.gov/pubmed/28503213
http://dx.doi.org/10.1186/s13148-017-0354-2

Ejemplares similares