Platelet desialylation is a novel mechanism and a therapeutic target in thrombocytopenia during sepsis: an open-label, multicenter, randomized controlled trial

BACKGROUND: Studies in murine models suggested that platelet desialylation was an important mechanism of thrombocytopenia during sepsis. METHODS: First, we performed a prospective, multicenter, observational study that enrolled septic patients with or without thrombocytopenia to determine the associ...

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Detalles Bibliográficos
Autores principales: Li, Mei-feng, Li, Xiao-li, Fan, Kai-liang, Yu, Ying-yi, Gong, Jing, Geng, Shu-ying, Liang, Ya-feng, Huang, Ling, Qiu, Ji-hua, Tian, Xing-han, Wang, Wen-ting, Zhang, Xiao-lu, Yu, Qing-xia, Zhang, Yuan-feng, Lin, Peng, Wang, Li-na, Li, Xin, Hou, Ming, Liu, Lu-yi, Peng, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426054/
https://www.ncbi.nlm.nih.gov/pubmed/28494777
http://dx.doi.org/10.1186/s13045-017-0476-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426054/
https://www.ncbi.nlm.nih.gov/pubmed/28494777
http://dx.doi.org/10.1186/s13045-017-0476-1

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