Knockdown of PRDX2 sensitizes colon cancer cells to 5-FU by suppressing the PI3K/AKT signaling pathway

Although, 5-Fluorouracil (5-FU) remains widely used in adjuvant therapy in patients with colon cancer, resistance to 5-FU-based chemotherapy is an important reason for treatment failure. Recent studies have reported that an enhanced reactive oxygen species (ROS) scavenging system shows drug resistan...

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Detalles Bibliográficos
Autores principales: Xu, Jun, Zhang, Shouru, Wang, Rong, Wu, Xingye, Zeng, Li, Fu, Zhongxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426286/
https://www.ncbi.nlm.nih.gov/pubmed/28432271
http://dx.doi.org/10.1042/BSR20160447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426286/
https://www.ncbi.nlm.nih.gov/pubmed/28432271
http://dx.doi.org/10.1042/BSR20160447

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