Knockdown of PRDX2 sensitizes colon cancer cells to 5-FU by suppressing the PI3K/AKT signaling pathway

Although, 5-Fluorouracil (5-FU) remains widely used in adjuvant therapy in patients with colon cancer, resistance to 5-FU-based chemotherapy is an important reason for treatment failure. Recent studies have reported that an enhanced reactive oxygen species (ROS) scavenging system shows drug resistan...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Jun, Zhang, Shouru, Wang, Rong, Wu, Xingye, Zeng, Li, Fu, Zhongxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426286/
https://www.ncbi.nlm.nih.gov/pubmed/28432271
http://dx.doi.org/10.1042/BSR20160447

Ejemplares similares

Ejemplares similares