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Model-free extraction of spin label position distributions from pseudocontact shift data

A significant problem with paramagnetic tags attached to proteins and nucleic acids is their conformational mobility. Each tag is statistically distributed within a volume between 5 and 10 Angstroms across; structural biology conclusions from NMR and EPR work are necessarily diluted by this uncertai...

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Detalles Bibliográficos
Autores principales: Suturina, Elizaveta A., Häussinger, Daniel, Zimmermann, Kaspar, Garbuio, Luca, Yulikov, Maxim, Jeschke, Gunnar, Kuprov, Ilya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426344/
https://www.ncbi.nlm.nih.gov/pubmed/28553510
http://dx.doi.org/10.1039/c6sc03736d