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Leukotriene A4 Hydrolase Genotype and HIV Infection Influence Intracerebral Inflammation and Survival From Tuberculous Meningitis

BACKGROUND. Tuberculous meningitis (TBM) is the most devastating form of tuberculosis, yet very little is known about the pathophysiology. We hypothesized that the genotype of leukotriene A(4) hydrolase (encoded by LTA4H), which determines inflammatory eicosanoid expression, influences intracerebral...

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Detalles Bibliográficos
Autores principales: Thuong, Nguyen T. T., Heemskerk, Dorothee, Tram, Trinh T. B., Thao, Le T. P., Ramakrishnan, Lalita, Ha, Vu T. N., Bang, Nguyen D., Chau, Tran T. H., Lan, Nguyen H., Caws, Maxine, Dunstan, Sarah J., Chau, Nguyen V. V., Wolbers, Marcel, Mai, Nguyen T. H., Thwaites, Guy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426373/
https://www.ncbi.nlm.nih.gov/pubmed/28419368
http://dx.doi.org/10.1093/infdis/jix050