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Dexmedetomidine Oral Mucosa Patch for Sedation Suppresses Apoptosis in Hippocampus of Normal Rats

PURPOSE: Dexmedetomidine, an α2-adrenergic agonist, provides sedative and analgesic effects without significant respiratory depression. Dexmedetomidine has been suggested to have an antiapoptotic effect in response to various brain insults. We developed an oral mucosa patch using dexmedetomidine for...

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Detalles Bibliográficos
Autores principales: Park, Je Hoon, Ko, Il Gyu, Kim, Sung Eun, Jin, Jun Jang, Hwang, Lakkyong, Kim, Chang Ju, Yoon, Soo Hwan, Hong, Jongki, Chung, Jun Young, Lee, Deok Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Continence Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426424/
https://www.ncbi.nlm.nih.gov/pubmed/28446017
http://dx.doi.org/10.5213/inj.1734884.442