A practical strategy to design and develop an isoform-specific fluorescent probe for a target enzyme: CYP1A1 as a case study

The development of isoform-specific probe(s) for a target enzyme with multiple homologs is always challenging. Herein, a practical strategy was used to design and develop an isoform-specific probe for CYP1A1, a key cytochrome P450 isoenzyme involved in xenobiotic metabolism and bioactivation. On the...

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Detalles Bibliográficos
Autores principales: Dai, Zi-Ru, Feng, Lei, Jin, Qiang, Cheng, Hailing, Li, Yan, Ning, Jing, Yu, Yang, Ge, Guang-Bo, Cui, Jing-Nan, Yang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426458/
https://www.ncbi.nlm.nih.gov/pubmed/28553516
http://dx.doi.org/10.1039/c6sc03970g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426458/
https://www.ncbi.nlm.nih.gov/pubmed/28553516
http://dx.doi.org/10.1039/c6sc03970g

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