Water permeation through the internal water pathway in activated GPCR rhodopsin

Rhodopsin is a light-driven G-protein-coupled receptor that mediates signal transduction in eyes. Internal water molecules mediate activation of the receptor in a rhodopsin cascade reaction and contribute to conformational stability of the receptor. However, it remains unclear how internal water mol...

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Detalles Bibliográficos
Autores principales: Tomobe, Katsufumi, Yamamoto, Eiji, Kholmurodov, Kholmirzo, Yasuoka, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426653/
https://www.ncbi.nlm.nih.gov/pubmed/28493967
http://dx.doi.org/10.1371/journal.pone.0176876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426653/
https://www.ncbi.nlm.nih.gov/pubmed/28493967
http://dx.doi.org/10.1371/journal.pone.0176876

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